Bisoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .
Bisoprolol is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart .
Bisoprolol is available only with your doctor's prescription .
Before Using bisoprolol
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For bisoprolol, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to bisoprolol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of bisoprolol in the pediatric population. Safety and efficacy have not been established .
Geriatric
Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of bisoprolol in the elderly .
Pregnancy
Pregnancy Category
Explanation
All Trimesters
C
Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Using bisoprolol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Albuterol
Amiodarone
Arformoterol
Bambuterol
Bitolterol
Broxaterol
Clenbuterol
Clonidine
Colterol
Diltiazem
Dronedarone
Fenoldopam
Fenoterol
Fentanyl
Formoterol
Hexoprenaline
Isoetharine
Levalbuterol
Metaproterenol
Pirbuterol
Procaterol
Reproterol
Rimiterol
Ritodrine
Salmeterol
Terbutaline
Tretoquinol
Tulobuterol
Verapamil
Using bisoprolol with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Acarbose
Acetohexamide
Alfuzosin
Amlodipine
Arbutamine
Benfluorex
Bunazosin
Chlorpropamide
Digoxin
Doxazosin
Felodipine
Gliclazide
Glimepiride
Glipizide
Gliquidone
Glyburide
Guar Gum
Insulin
Insulin Aspart, Recombinant
Insulin Glulisine
Insulin Lispro, Recombinant
Lacidipine
Lercanidipine
Manidipine
Metformin
Methyldopa
Mibefradil
Miglitol
Moxisylyte
Nicardipine
Nifedipine
Nilvadipine
Nimodipine
Nisoldipine
Nitrendipine
Phenoxybenzamine
Phentolamine
Pranidipine
Prazosin
Repaglinide
Rifapentine
St John's Wort
Tamsulosin
Terazosin
Tolazamide
Tolbutamide
Trimazosin
Troglitazone
Urapidil
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of bisoprolol. Make sure you tell your doctor if you have any other medical problems, especially:
Angina (severe chest pain)—May provoke chest pain if stopped too quickly .
Blood vessel disease—Use with caution. bisoprolol may make this condition worse .
Bradycardia (slow heartbeat) or
Heart block or
Heart failure—Should not use in patients with these conditions .
Diabetes or
Hyperthyroidism (overactive thyroid) or
Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat .
Kidney disease or
Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body .
Lung disease (e.g., asthma, bronchitis, emphysema)—May cause difficulty with breathing in patients with this condition .
Bisoprolol Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Body aches or pain
chest pain
chills
cough
difficult or labored breathing
ear congestion
fever
headache
loss of voice
nasal congestion
pain or tenderness around eyes and cheekbones
shortness of breath or troubled breathing
sneezing
sore throat
stuffy or runny nose
tightness in chest
unusual tiredness or weakness
wheezing
Rare
Chest discomfort
lightheadedness, dizziness, or fainting
slow or irregular heartbeat
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Anxiety
blurred vision
cold sweats
coma
confusion
cool, pale skin
decreased urine output
depression
dilated neck veins
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
extreme fatigue
fast heartbeat
increased hunger
irregular breathing
nausea
nervousness
nightmares
noisy breathing
seizures
shakiness
slurred speech
sweating
swelling of face, fingers, feet, or lower legs
weight gain
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Abnormal or decreased touch sensation
diarrhea
difficulty in moving
lack or loss of strength
muscle pain or stiffness
pain in joints
sleeplessness
trouble sleeping
unable to sleep
vomiting
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.